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Kidney stone facts A kidney stone is a hard, crystalline mineral material formed within the kidney or urinary tract. Nephrolithiasis is the medical term for kidney stones. Symptoms of a kidney stone include flank pain (the pain can be quite severe) and blood in the urine (hematuria). Kidney stones form when there is a decrease in urine volume and/or an excess of stone-forming substances in the urine. Dehydration is a major risk factor for kidney stone formation. People with certain medical conditions,
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