Second Son is set seven years after the good ending of Infamous 2, in which Cole MacGrath activated the Ray Field Inhibitor (RFI) to destroy a Conduit (super-humans named for their ability to "channel" powers) named John White, also known as the Beast and cure the Plague. The explosion that resulted was originally thought to have killed all Conduits across the globe; however, those outside of the blast radius or with a natural resistance have survived. Fearing the Conduits' abilities after th
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