Euthyroid sick syndrome, sick euthyroid syndrome, non-thyroidal illness syndrome or low T3 low T4 syndrome is a state of adaptation or dysregulation of thyrotropic feedback control[1] where the levels of T3 and/or T4 are at unusual levels, but the thyroid gland does not appear to be dysfunctional. This condition is often seen in starvation or critical illness.Ill patients may have normal to low TSH depending on the spectrum of illness. Total T4 and T3 levels may be altered by binding protein abnormalities,
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